Navidence and Datavant Sign Partnership to License Computable Operational Definition Libraries for In-study Design
New York, NY and Aurora, CO – March 4, 2026 — Datavant, the data collaboration platform trusted for healthcare and Navidence, a technology company focused supporting researchers in defining health data through the deployment of Computable Operational Definitions (CODefs), today announced a partnership to help life sciences organizations more precisely define study criteria and move more efficiently from protocol development to real-world evidence (RWE) generation.
Through this collaboration, Navidence’s CODef libraries will be integrated into Datavant’s trusted end-to-end healthcare data platform, enabling standardized, computable study definitions to be consistently applied across real-world datasets within a secure environment.
As the life sciences industry is increasingly embracing the use of real-world data (RWD), researchers face growing complexity in translating protocol-defined study criteria into standardized, computable logic. Defining diseases, treatments, and other key study variables often requires assembling and validating detailed code lists and algorithms across epidemiology, data science, informatics, and biostatistics teams. These efforts can take weeks and require coordination across multiple functions, slowing study startup and introducing variability in how key concepts are defined and applied across studies and datasets.
Founded in 2022, Navidence offers AI-native technology and professional services that make it radically more efficient to design and deploy clinical research studies using RWD through the use of CODefs—standardized, human and computer readable definitions of key study elements, including code lists—creating a bridge between clinical healthcare and research while providing the consistency, precision, efficiency, and trust demanded by regulatory agencies.
“There’s an enormous opportunity to unlock and increase the use of real-world data by more precisely aligning that data to our research questions, ” said Aaron Kamauu, CEO and co-founder of Navidence. “With this partnership with Datavant, we are able to integrate our CODefs to reduce the burden and increase the precision of defining what researchers need from RWD and allow Datavant’s analytics solutions to evaluate their robust RWD ecosystem to meet those research use cases.”
Datavant’s end-to-end healthcare data platform encompasses more than 350 data partners and 80,000 U.S. hospitals and clinics, providing secure access to real-world datasets across care settings. Across this broad data network, a curated, reusable source of truth for defining diseases, treatments, and clinical measures enables standardized study criteria to inform data evaluation, cohort identification, and RWE generation workflows—supporting a more consistent and rigorous approach to evidence development across studies and teams.
“As RWD networks expand, the ability to define and operationalize study criteria becomes foundational to effective insights and evidence generation,” said Sara Livengood, SVP of Life Sciences Product at Datavant. “Our end-to-end platform enables life sciences teams to securely source, link, and analyze RWD at scale. With the inclusion of Navidence’s curated CODef libraries, that workflow becomes more tightly aligned from study intent through data activation, helping produce evidence more consistently across a diverse set of studies and research questions.”
About Navidence
Navidence is a company that helps healthcare and life sciences organizations design and assess the use of real-world data in clinical research studies and clinical trials. Through its platform and Computable Operational Definitions (CODefs), Navidence enables consistent, transparent, and reproducible analysis of complex real-world data to support smarter research and better patient outcomes. To learn more about Navidence, visit www.navidence.com and follow us on LinkedIn.
About Datavant
Datavant is the data collaboration platform trusted for healthcare. With a mission to make the world’s health data secure, accessible, and actionable, Datavant works with payers, providers, life sciences, legal and insurance clients globally to accelerate insights. Datavant enables more than 60 million healthcare records to move between thousands of organizations across the healthcare ecosystem, more than 80,000 hospitals and clinics, 75% of the 100 largest health systems, and 350+ real-world data partners. Datavant has office locations in Boston, New York and San Diego, with international offices in Barcelona and Galway. To learn more about Datavant, visit www.datavant.com and follow us on LinkedIn.
