Research & Publications

Study in JACC examines finerenone’s effects on cardiorenal outcomes in patients with type 2 diabetes and chronic kidney disease, offering new insights for treatment.

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Kidney and Cardiovascular Effectiveness of SGLT2 Inhibitors vs GLP-1 Receptor Agonists in Type 2 Diabetes

Using Datavant's Death Index database, researchers assess COVID-19 mortality trend by time and sex to analyze mortality cases and identify observed differences.

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Sex differences in COVID-19 mortality: A large US-based cohort study (2020–2022)

Study analyzes the relationship between working memory and eating behavior, showing that cognitive capacity influences dietary self-control and unhealthy food choices.

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Adherence and persistence to tafamidis treatment among Medicare beneficiaries in the presence of a patient assistance program

Study in JAMA Network Open examines trends in financial toxicity among US cancer survivors from 2010 to 2022, highlighting persistent disparities by income and race.

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Privacy preserving record linkage for public health action: opportunities and challenges

WeSMA trial used privacy-preserving tokenization to link clinical trial participants with real-world data, enhancing data integration while protecting privacy.

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Using privacy-preserving record linkage to incorporate real-world data into a Phase IV long-term follow-up of individuals with SMA (WeSMA)

Large cohort study finds fewer than 25% of people with type 2 diabetes receive recommended CKD screening; treatment gaps identified in those with existing disease.

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Concordance With Screening and Treatment Guidelines for Chronic Kidney Disease in Type 2 Diabetes

This cohort study examines US county-level factors linked to disparities in maternal morbidity, highlighting associations with healthcare access, social vulnerability, and race.

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Development of a Longitudinal Prostate Cancer Transcriptomic and Clinical Data Linkage

Study analyzes geographic atrophy lesion growth in AMD using deep learning, highlighting variable progression rates and implications for clinical trial design.

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Prediction models for glaucoma in a multicenter electronic health records consortium: the Sight Outcomes Research Collaborative

Real-world study links higher SARS-CoV-2 spike antibody levels to reduced risk of symptomatic and severe COVID-19, supporting antibody use in risk assessment.

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Higher SARS-CoV-2 spike antibody levels are associated with reduced risk of subsequent symptomatic and severe COVID-19: A real-world data study

Oncology study finds over 90% mortality capture using combined real-world sources; NDI adds little value for OS estimates in GBM and pancreatic cancer

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Fit-for-purpose and scalable strategy to address mortality completeness for oncology research: Comparison of multiple real-world sources with the National Death Index

Study evaluates the impact of SGLT2 inhibitors on cardiac remodeling in heart failure patients, showing benefits in left ventricular structure and function.

Publication

Kidney and Cardiovascular Effectiveness of Empagliflozin Compared With Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes

This study outlines a method for updating age-constrained thresholds using upcoming 2020 census data and provides recommendations based on the 2010 census.

Publication

Best Practices in Evolving Privacy Frameworks for Patient Age Data: Census Data Study

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