Powerful Data Logistic Solutions for Health Plans
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Research and publications
See using real-world data for predictive modeling, benchmarking, and cross-disciplinary studies.
Adherence and persistence to tafamidis treatment among Medicare beneficiaries in the presence of a patient assistance program
Privacy-Preserving Record Linkage as a Valuable Method to Build More Complete Treatment Journeys
Data linkage multiplies research insights across diverse healthcare sectors
Data Linkage Multiplies Research Insights Across Diverse Healthcare Sectors
Many individuals experience ongoing symptoms following the onset of COVID-19, characterized as postacute sequelae of SARS-CoV-2 or post–COVID-19 condition (PCC). Less is known about the long-term outcomes for these individuals.
One-Year Adverse Outcomes Among US Adults With Post–COVID-19 Condition vs Those Without COVID-19 in a Large Commercial Insurance Database
The National COVID Cohort Collaborative (N3C) is an open science effort led by the NIH National Center for Advancing Translational Sciences aimed at accelerating COVID-19 research
Use of large-scale privacy protecting record linkages for data sharing to enhance
This article describes the implementation of a privacy-preserving record linkage (PPRL) solution across PCORnet®, the National Patient-Centered Clinical Research Network.
Assessing the impact of privacy-preserving record linkage on record overlap and patient demographic and clinical characteristics in PCORnet®, the National Patient-Centered Clinical Research Network
The aim of this study was to determine whether a secure, privacy-preserving record linkage (PPRL) methodology can be implemented in a scalable manner for use in a large national clinical research network.
Establishing a framework for privacy-preserving record linkage among electronic health record and administrative claims databases within PCORnet
This year, a study of ten million people revealed the power of longitudinal research. A team mined a vast medical database of US military personnel, including tissue samples and health records collected over 20 years.
Cancer Research Needs Better Databases
To learn from the evolving lessons of addressing the COVID-19 pandemic and to bolster the future use of real-world data (RWD) and real-world evidence (RWE), The FDA Foundation, in collaboration with the International Society for Pharmacoepidemiology (ISPE), created The COVID-19 Real-World Evidence Primer.
Real-World Evidence Primer
Elmer V Bernstam, Reuben Joseph Applegate, Alvin Yu, Deepa Chaudhari, Tian Liu, Alex Coda, Jonah Leshin. Objective: Our objective was to evaluate tokens commonly used by clinical research consortia to aggregate clinical data across institutions.
Real-World Matching Performance of Deidentified Record-Linking Tokens
Wataru Ando, Takeshi Horii, Takayuki Uematsu, Hideaki Hanaki, Koichiro Atsuda & Katsuya Otori. The impact of overlapping risk factors on coronavirus disease (COVID-19) severity is unclear. To evaluate the impact of type 2 diabetes (T2D) and obesity on COVID-19 severity, we conducted a cohort study with 28,095 anonymized COVID-19 patients using data from the COVID-19 Research Database from January 1, 2020 to November 30, 2020.
Impact of overlapping risks of type 2 diabetes and obesity on coronavirus disease severity in the United States
Jacob Wallace, PhD; Anthony Lollo, PhD; Chima D. Ndumele, PhD. In the US, COVID-19 is responsible for hundreds of thousands of excess deaths,1 which has led to considerable interest in strategies to mitigate its impact.
Evaluation of the Association Between Medicare Eligibility and Excess Deaths During the COVID-19 Pandemic in the US
Jane M. Zhu, Renae Myers, K. John McConnell, Ximena Levander, and Sunny C. Lin. The COVID-19 pandemic disrupted mental health services delivery across the US, but the extent and implications of these disruptions are unclear.
Trends In Outpatient Mental Health Services Use Before And During The COVID-19 Pandemic
Amivantamab is an epidermal growth factor receptor (EGFR)-MET bispecific antibody with immune cell-directing activity.
Amivantamab compared with real-world therapies in patients with NSCLC with EGFR Exon 20 insertion mutations who have progressed after platinum doublet chemotherapy
William E. Trick, Fred Rachman, Keiki Hinami, Jennifer C. Hill, Craig Conover, Lisa Diep, Howard S. Gordon, Abel Kho, David O. Meltzer, Raj C. Shah, Ed Stellon, Padma Thangaraj & Peter S. Toepfer
Variability in comorbidities and health services use across homeless typologies: multicenter data linkage between healthcare and homeless systems
Constantina Boikos, Lauren Fischer, Dan O’Brien, Joe Vasey, Gregg C Sylvester, James A Mansi. This study estimated the relative vaccine effectiveness (rVE) of ccIIV4 versus egg-derived inactivated quadrivalent influenza vaccine (eIIV4) in preventing influenza-related medical encounters in the 2018–2019 US season.
Relative Effectiveness of the Cell-derived Inactivated Quadrivalent Influenza Vaccine Versus Egg-derived Inactivated Quadrivalent Influenza Vaccines in Preventing Influenza-related Medical Encounters During the 2018–19 Influenza Season in the US
Aaron Baum
Primary Care in the COVID-19 Pandemic: Chronic Care Management During the COVID-19 Pandemic
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