Resource Library | Datavant

The United States’ healthcare system is one of the most technically advanced in the world, yet it struggles to answer even simple questions about COVID-19 due to the remarkable fragmentation if its health data. This panel will highlight examples of effective data sharing in the wake of the pandemic as well as the myriad missed opportunities for collaboration.

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How Data Sharing Can Help Us Better Understand COVID-19

Given the intense focus on the development of COVID-19 vaccines, clinical trials emerged at the forefront of the national conversation. This also brought increased interest in “Decentralized Clinical Trials” (DCTs): technology and practices that allow for more patient-centric trial operations.

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Decentralized Clinical Trials: The Bridge Between Trials and Real World Evidence

Health and healthcare disparities are driven by complex and interlocking factors within and beyond systems of care. In the wake of COVID-19, the new and long-standing disparities in healthcare access, delivery, and outcomes are increasingly evident.

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Better Serving Vulnerable Populations and Managing Health Disparities

By virtue of sheer volume, oncology trials can set the stage for overall clinical trial innovation. Moreover, oncology as a therapeutic area has seen the closest interplay between clinical trial data and real-world data, from the creation of external control arms created exclusively with real-world data, to long-term follow-up registries, to pragmatic clinical trials.

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Advancing Oncology Clinical Trials with Real-World Data

Moderated by Jules Polonetsky, Speakers: Inderpal Bhandari, Knut Mager, Kathryn Marchesini, Deven McGraw

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Putting the Patient First: Health Data Ethics, Technology & Consent

Speaker: Senator Tom Daschle, Founder & CEO, The Daschle Group & Former Senate Majority Leader, Steve Swank, Chief Business Officer, Datavant

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Opening Remarks 2019

Moderated by Holly May, Speaker: Amy Abernethy

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Keynote: The Future of Health Data at the FDA

Moderated by Sam Roosz, Speaker: Janet Woodcock

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Keynote: FDA’s Use of and Guidance on Real-World Data

The success of a clinical trial depends on access to the right data at the right time. But how can researchers securely connect and enrich trial data while maintaining patient privacy?

Ebook

How-To Guide: Navigating Clinical Trial Tokenization & Data Linkage

In today’s dynamic regulatory environment, healthcare, life science, and research organizations must balance patient privacy with the need for innovation.

Ebook

Ensuring privacy and compliance across health data

Experts provide overview of key health data sources, such as EHRs, claims, lab, and genomics. Effectively use diverse health data in research and operations.

Ebook

Ecosystem Explorer: Expert Interviews on the Most Common and Useful Data Types in the Datavant Ecosystem

Leverage patient-authorized data to advance research and development efforts. Datavant helps Sponsors find fit-for-purpose data partners for their trial needs.

Ebook

A New Role for Real-World Data in Clinical Trials: Patient Authorized Workflows

Checklist for providers to respond to payer requests. Avoid unnecessary rework, additional payer fees, or penalties to focus on providing patient-centered care.

Ebook

Denials Checklist

Explore the transformative power of connected real-world data in reshaping how life sciences companies approach audience targeting, engagement, and measurement.

Ebook

Measuring Impact with Real-World Data

In today's clinical research landscape, patient registries are transforming how we understand diseases and develop new treatments.

Ebook

How to build a patient registry

Tokenizing clinical trial data in the development lifecycle allows earlier access to real-world data. Validate populations prior to marketing authorization.

Ebook

The Utility of Data Tokenization in Clinical Trials

Specialty drugs drive the majority of prescription drug spending. Learn about capabilities unlocked by connecting SP data, first party data, and RWD.

Ebook

Linking Specialty Pharmacy Data for Commercial Success: The New World of Commercial Analytics

Learn how consulting and professional services can harness de-identified health data to power analytics for their organizations and clients.

Ebook

Connecting Health Data for Stronger Analytics and Deeper Insights: Consulting & Professional Services Edition

To build the best predictive models, companies need access to massive amounts of data – ideally longitudinal data about a patient’s journey through the health system.

Ebook

How to Find and Connect the Right Health Data for Stronger Predictive Analytics

De-identify data while balancing business needs, research objectives and, patient privacy protections. Learn how to protect sensitive information.

Ebook

HIPAA Compliant De-identified Healthcare Data Exchange

Clinical trials are central to making health advancements. Clinical trial tokenization and real-world data enable improved insights into the patient journey.

Ebook

Linking Clinical Trials to Real-World Data: 7 Sample Use Cases

Link clinical trial data to real world data sources and establish a more complete picture of each study participants’ health journey.

Ebook

How-to Guide: Readying Your Clinical Trial for Linkage with Real-World Data

Learn about our four step process for getting your EHR data migrated to a new system. Migrate in 60 days or less, without disruption to your practice.

Ebook

Migrating Your EHR Data Without Disruption

See how Southwest General Health Center strengthened coding quality and operational efficiency through a strategic partnership with Datavant.

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Building a Trusted Partnership for Coding Excellence with Southwest General Health Center

Discover how Arkansas Blue Cross Blue Shield transformed its risk adjustment and care coordination efforts using Datavant’s Clinical Data Platform for real-time, structured clinical data acquisition.

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The Power of Seamless Data Exchange in Healthcare

Learn how researchers accessed datasets with national scope and was near real-time to guide healthcare policy-makers into saving lives from COVID-19.

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How 100M+ EHR Records Accelerated COVID-19 Analysis

Kythera Labs leveraged Datavant's advanced identity resolution technology to narrow the number of distinct patients, producing a higher quality dataset.

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Case Study: The power of patient matching in real-world data

Linking curated claims and registry data from electronic health records sheds light on full disease burden and healthcare utilization

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The Picture Comes into Focus for Patients Suffering with Rare Eye Disease

A molecular diagnostics company developed a blood test to support treatment selection for patients with advanced non-small cell lung cancer (NSCLC).

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Linking Oncology Diagnostic Labs to Assess their Effectiveness in Supporting Immunotherapy Treatment Selection in Lung Cancer

Despite high effectiveness of COVID-19 vaccines in the real-world, there have been cases of fully vaccinated patients contracting COVID.

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Validating an Antibody Test to Predict Infection Rates in COVID-19

A biopharma company was conducting a Phase III study to assess the safety and effectiveness of a new COVID-19 vaccine. They needed to identify and connect to real-world data sources that would enable observation of infection rates and adverse events beyond the period of the trial.

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Trial Tokenization to Understand the Long Term Effectiveness of a New COVID-19 Vaccine

A top 20 pharma company noticed that a significant portion of patients who were on an infusion therapy had stopped treatment. This happened despite patients receiving support through a variety of assistance programs.

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How One Pharma Used Connected Specialty Drug Data and RWD to Improve Patient Adherence

A major pharma company had developed a treatment for a rare condition. However, two years after launch, the drug’s sales were far below expectations. Finding eligible patients for this new treatment was proving difficult because disease symptoms are heterogenous and patients can go years before being diagnosed correctly.

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How One Pharma Connected Specialty Drug Data for Better Physician Targeting

Connecting data at the patient level is critical in gaining a deep, longitudinal view of how different interventions and policies can affect patient outcomes. The following peer-reviewed articles provide detail on studies using health data connected by Datavant technology.

Case study

Research Using Health Data Connected by Datavant

A pharma client partnered with an Advanced Analytics company to develop a model to identify patients likely to have hereditary ATTR amyloidosis.

Case study

Profiling and Diagnosing Rare Disease Patients

Recently, a biopharmaceutical company completed at 36 week Phase IV study of 175 patients across 40 trial sites to evaluate the effectiveness and safety of a recently approved anti-seizure medication as adjunctive therapy in focal seizure. Patient retention was the primary efficacy endpoint and seizure frequency was a secondary efficacy endpoint.

Case study

Trial Tokenization and Linking to Real World Data: Extending the effectiveness and safety analysis of a new focal seizure treatment

Recruiting patients for Nonalcoholic fatty liver disease (NAFLD) and Non-alcoholic steatohepatitis (NASH) trials can be a challenge. Diagnosis and staging require a combination of lab test results combined to create a Fibrosis-4 score (FIB-4) and specialized MRI and ultrasound liver imaging to measure hepatic steatosis, and liver stiffness.

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Overcoming Trial Recruitment Challenges in NASH Using De-identified Patient Linking

Building External Control Arms through Real-World Data - A Phase II Oncology Case Study

Case study

Linking EHR, Genomic & Claims Data to Find Ultra-Rare Disease Patients

Download this overview to learn how Datavant powers external control arms and why they are important, using an oncology case study as an example.

Case study

External Control Arms Overview

There was a customized process in place to fulfill managed care audits; however, as is the case with many “workarounds,” the solution did not take full advantage of technology and best practices.

Case study

Provider Payer Collaboration Changes the Game for Managed Care Audit Processing

Nicklaus Children’s Hospital implemented Patient Request to allow families to request medical records anytime, from anywhere – even after the HIM department closed due to COVID.

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How Nicklaus Children’s Hospital Uses HealthSource Patient Request to Improve Patient Access to Health Information

In the rapidly evolving life sciences ecosystem, where data is the lifeblood of research, development , and patient care, ensuring quality and compliance is paramount and goes far beyond simply ticking boxes on a checklist.

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